•‹³@@‰Ζϊ± ‚Žu@@iTakashi IEZAKI, PhDj

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2011”N ‹ΰ‘ς‘εŠw–ςŠw•”‘n–ς‰ΘŠw‰Θ‘²‹Ζ
2013”N ‹ΰ‘ς‘εŠw‘εŠw‰@ˆγŠwŒnŒ€‹†‰Θ‘n–ς‰ΘŠwκUi”ŽŽm‰Ϋ’φ‘OŠϊjC—Ή
2016”N ‹ΰ‘ς‘εŠw‘εŠw‰@ˆγ–ς•ΫŒ’Šw‘‡Œ€‹†‰Θ‘n–ς‰ΘŠwκUi”ŽŽm‰Ϋ’φŒγŠϊjC—Ή
2016”N-2019”N ‹ΰ‘ς‘εŠwζ’[‰ΘŠwƒCƒmƒx[ƒVƒ‡ƒ“„i‹@\@”ŽŽmŒ€‹†ˆυ
2019”N-2020”N •Δ‘ƒ\[ƒNŒ€‹†ŠiSalk Institute for Biological Studiesj@Postdoctoral fellow
2020”N-2022”N Šς•Œ–ς‰Θ‘εŠw‹@”\•ͺŽqŠw‘εuΐ–ς—ŠwŒ€‹†ŽΊ@•‹³
2022”N5ŒŽ-Œ»έ ˆ€’mˆγ‰Θ‘εŠwˆγŠw•”Ά—Šwuΐ@•‹³

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  1. SMURF2 phosphorylation at Thr249 modifies glioma stemness and tumorigenicity by regulating TGF-β receptor stability.
    Hiraiwa M, Fukasawa K, Iezaki T, Sabit H, Horie T, Tokumura K, Iwahashi S, Murata M, Kobayashi M, Suzuki A, Park G, Kaneda K, Todo T, Hirao A, Nakada M, Hinoi E.
    Communications Biology 5(1):22, 2022.
  2. αKLOTHO and sTGFβR2 treatment counteract the osteoarthritic phenotype developed in a rat model.
    Martinez-Redondo P, Guillen-Guillen I, Davidsohn N, Wang C, Prieto J, Kurita M, Hatanaka F, Zhong C, Hernandez-Benitez R, Hishida T, Lezaki T(Iezaki T), Sakamoto A, Nemeth AN, Hishida Y, Esteban CR, Shojima K, Huang L, Shokhirev M, Nuñez-Delicado E, Campistol JM, Guillen-Vicente I, Rodriguez-Iñigo E, Lopez-Alcorocho JM, Guillen-Vicente M, Church G, Reddy P, Guillen-Garcia P, Liu GH, Belmonte JCI.
    Protein & Cell 11(3): 219-226, 2020.
  3. The L-type amino acid transporter LAT1 inhibits osteoclastogenesis and maintains bone homeostasis through the mTORC1 pathway.
    Ozaki K, Yamada T, Horie T, Ishizaki A, Hiraiwa M, Iezaki T, Park G, Fukasawa K, Kamada H, Tokumura K, Motono M, Kaneda K, Ogawa K, Ochi H, Sato S, Kobayashi Y, Shi YB, Taylor PM, Hinoi E.
    Science Signaling 12(589): eaaw3921, 2019.
  4. mTORC1 Activation in Osteoclasts Prevents Bone Loss in a Mouse Model of Osteoporosis.
    Hiraiwa M, Ozaki K, Yamada T, Iezaki T, Park G, Fukasawa K, Horie T, Kamada H, Tokumura K, Motono M, Kaneda K, Hinoi E.
    Frontiers in Pharmacology 10:684, 2019.
  5. Hypoxia affects Slc7a5 expression through HIF-2α in differentiated neuronal cells.
    Onishi Y, Hiraiwa M, Kamada H, Iezaki T, Yamada T, Kaneda K, Hinoi E.
    FEBS Open Bio 9(2): 241-247, 2019.
  6. Translational Control of Sox9 RNA by mTORC1 Contributes to Skeletogenesis.
    Iezaki T, Horie T, Fukasawa K, Kitabatake M, Nakamura Y, Park G, Onishi Y, Ozaki K, Kanayama T, Hiraiwa M, Kitaguchi Y, Kaneda K, Manabe T, Ishigaki Y, Ohno M, Hinoi E.
    Stem Cell Reports 11(1): 228-241, 2018.
  7. The MAPK Erk5 is necessary for proper skeletogenesis involving a Smurf-Smad-Sox9 molecular axis.
    Iezaki T, Fukasawa K, Horie T, Park G, Robinson S, Nakaya M, Fujita H, Onishi Y, Ozaki K, Kanayama T, Hiraiwa M, Kitaguchi Y, Kaneda K, Yoneda Y, Takarada T, Guo XE, Kurose H, Hinoi E.
    Development (Cambridge, England). 145(14): dev164004, 2018.

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